Publications


  • Minas W. & J.E. Bailey (1995) Co-overexpression of PrlF increases cell viability and enzyme yields in recombinant Escherichia coli expression Bacillus stearothermophilus a-amylase. Biotechnol. Prog. 11:403-411.[Medline]

    Cohen G., Or E., Minas W. & Sternberg N.L. (1996) The bacteriophage P1 lytic replicon: directionality of replication and cis - acting elements. Gene 175:151-155.[Medline]

    Minas, W. (1997) Fascination Streptomyces. Biowold 5:14-17.

    Minas W., Brünker P., Kallio P.T. & Bailey J.E. (1998) Improved erythromycin production in a genetically engineered industrial strain of Saccharopolyspora erythraea. Biotechnol. Prog., 14(4):561-566.[Medline]

    Brünker P., Minas W., Kallio P.T. & Bailey J.E. (1998) Genetic engineering of an industrial strain of Saccharopolyspora erythraea for stable expression of the Vitreoscilla hemoglobin gene. Microbiol. 144:2441-2448.[Medline]

    Brünker P., McKinney K., Sterner O., Minas W. & Bailey J.E. (1999) Isolation and characterization of the naphthocyclinone gene cluster from Streptomyces arenae DSM 40737 and heterologous expression of the polyketide synthase genes. Gene 227:125-135. [Medline]

    Brünker P., Minas W., Kallio P. & Bailey J.E. (1999) Methods and compositions for increasing production of erythromycin. United States Patent Nr. 5,908,764.[Medline]

    Clerval R., Kühner M., Li Z., Minas W., Fjällman A., Witholt B. & Duetz W. (2000) High throughput screening of wild-type microbial strains. Bioworld 6:24-27

    Minas, W., Bailey J.E. & Duetz W. (2000) Steptomyces in micro-cultures: Growth, production of secondary metabolites, and storage and retrieval in the 96 well format. Ant. Leeuven. 78:297-305. [Medline]

    Martin R., Sterner O., Alvarez M.A., De Clercq E., Bailey J.E. & Minas W. (2001) Collinone, a new recombinant angular polyketide antibiotic made by an engineered Streptomyces strain. J. Antibiot. 54(3): 239-249. [Medline]

    Duetz W., Minas W., Kühner M., Clerval R., Li Z., Fjällman A. & Witholt B. (2001). Use of miniaturised growth systems for the screening of secondary metabolites and microbial enzymes. Biowold 2:6-8.

    Brünker, P., Sterner O., Bailey J.E. & Minas W. (2001) Heterologous expression of the naphthocyclinone hydroxylase gene from Streptomyces arenae for production of novel hybrid polyketides. Ant. Leeuven. 79:235-245. [Medline]

    Viollier P. H., Nguyen K.T., Minas W., Folcher M., Dale G.E., & Thompson C.J. (2001) The role of the aconitase in growth, metabolism, and morphological differentiation of Streptomyces coelicolor. J. Bacteriol. 183:3193-3203. [Medline]

    Viollier P. H., Minas W., Dale G.E., Folcher M. & Thompson C.J. (2001) The role of acid metabolism in Streptomyces coelicolor morphological differentiation and antibiotic biosynthesis. J. Bacteriol. 183:3184-3192. [Medline]

    Hecht K., Bailey J. E. & Minas W. (2002) Polycistronic Gene Expression in Yeast versus Cryptic Promoter Elements. FEMS Yeast Research 2:215-224. [Abstract]

    Minas W. (2002) Metabolic engineering of secondary metabolite biosynthesis: Opportunities and limitations. Chimica oggi 20:52-59. [Abstract]

    Novotna J., Vohradsky J., Berndt P., Gramajo H., Langen H., Li X. M., Minas W., Orsaria L., Roeder D. & Thompson C. J. (2003) Proteomic studies of diauxic lag in the differentiating prokaryote Streptomyces coelicolor reveal a regulatory network of stress induced proteins and central metabolic enzymes. Mol. Microbiol. 48(5):1289-303. [Full Text]

    Barber M.S., Giesecke U., Reichert A. & Minas W. (2004). Industrial Enzymatic Production of Cephalosporin-Based b-Lactams. In: Brakhage A., Scheper T. (eds.) Adv Biochem Engin/Biotechnol, 88:197-215. [Abstract]

    Minas W. (2005) Production of Erythromycin with Saccharopolyspora erythraea. In: Methods in Biotechnology, Vol. 18: Microbial Processes and Products, Barredo JL(ed), Humana Press Inc., p65-90

    Valsesia G., Medaglia G., Held M., Minas W., & Panke S. (2007). Circumventing the effect of product toxicity: development of a novel two-stage production process for the lantibiotic gallidermin. Appl. Environ. Microbiol. 73:1635-1645. [Abstract]

    Minas W. (2008) Production of Erythromycin With Saccharopolyspora erythraea. In: Flickinger M.C., Drew S.W., Spier R.E. (eds.) Encyclopedia of Industrial Biotechnology: Bioprocess, Bioseparation, and Cell Technology, Humana Press Inc. p65-89

    Minas W. (2009) Erythromycins. In: Barredo J.L. (ed.) Methods in Biotechnology, vol. 18: Microbial Products and Processes, John Wiley and Sons, Inc p65-89; [Abstract]

    Hans-Peter Meyer, Wolfgang Minas, Diego Schmidhalter (2016) Industrial-Scale Fermentation. In: Wittmann C., Liao J.C.(eds.) In: Industrial Biotechnology, Wiley and Sons, [Abstract]

    Babu Halan & Wolfgang Minas (2019) Continuous Bioprocessing Promises and Challenges. BioProcess International 18(3)e1 February 2020 E-Book, [Abstract]





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    updated November 2020